Department for biomaterials research

Recent projects

Jouvenile Diabetes Research Foundation. JDRF Grant

New generation PMCG multicomponent microcapsule with tailored biointerface to avoid the immune response after transplantation
Project JDRF
Principal investigator: Igor Lacík
Registration number: 2-SRA-2018-521-S-B
Duration of the project: 09.2017 - 08.2019
Cooperating institutions: CellTrans, Inc., Chicago, USA (Prof Oberholzer), NTNU Trondheim, Norway, UMCh Praha, CZ

Slovak Research and Development Agency (APVV)

Gold nanoparticles: impact of physico-chemical properties on distribution, accumulation and long-term toxicity in vivo(BIONANOGOLD)
Project APVV
Principal investigator: Filip Rázga
Registration number: APVV-16-0579
Duration of the project: 07.2017 - 06.2021
Cooperating institutions: Biomedical research Center SAS (Andrea Bábelová)

Multivalent morpholino-based antisense system for CML(MOR4CML)
Project APVV
Principal investigator: Filip Rázga
Registration number: APVV-15-0215
Duration of the project: 07.2016 - 06.2020
Cooperating institutions: Biomedical research Center SAS

Nanocomposite materials based on organo-phosphonium smectits and polymers(Nanomat)
Project APVV
Principal investigator: J. Kronek
Registration number: APVV-15-0741
Duration of the project: 07.2016 - 06.2020
Cooperating institutions: Ústav anorganickej chémie SAV

Vysoko selektívna liečba nádorových ochorení: komplexy endogénnych lipoproteínov s DARPinmi ako nová generácia transportných systémov pre cielený transport liečiv(DARLINK)
Project APVV
Principal investigator: I. Lacík
Registration number: APVV-15-0485
Duration of the project: 07.2016 - 06.2020
Cooperating institutions: Prírodovedecká fakulta UPJŠ

Materials and processes for functional encapsulation of pancreatic islets in diabetes treatment(MEREDIT)
Project APVV
Principal investigator: Igor Lacík
Registration number: APVV-14-0858
Duration of the project: 07.2015 - 06.2019
Cooperating institutions: International laser centre

Scientific Grant Agency (VEGA)

Modeling and synthesis of hybrid conjugated systems for anticancer therapy
Project VEGA
Principal investigator: Filip Rázga
Registration number: VEGA 2/0094/15
Duration of the project: 01.2015 - 12.2018

Mechanisms of gold and magnetite nanoparticles effects on renal cells.
Project VEGA
Principal investigator: Filip Rázga
Registration number: VEGA 2/0113/15
Duration of the project: 01.2015 - 12.2018
Cooperating institutions: Institute of Experimental Oncology SAS (A. Bábelová)

Preparation of polymeric microspheres via internal gelation in emulsion and critical evaluation of their properties toward functional treatment of type I diabetes
Project VEGA
Principal investigator: Dušana Treľová
Registration number: VEGA 2/0059/16
Duration of the project: 01.2016 - 12.2018

Previous projects

BASF

Determination of rate coefficients of water-soluble monomers with special emphasis on charged/ionizable monomers
Project BASF
Principal investigator: Igor Lacík
Registration number: BASF 06/2004
Duration of the project: 06.2004 - 05.2015
Cooperating institutions: Institute of Physical Chemistry, Göttingen, Germany (Prof. M. Buback), Queen's University, Kingston (Prof. R. Hutchinson) and Eidgenössische Technische Hochschule, Zürich, Switzerland (Prof. G. Storti)

Jouvenile Diabetes Research Foundation. JDRF Grant

Multicomponent microcapsules for allogeneic islet transplantation in a comprehensive, preclinical non-human primate model
Project JDRF
Principal investigator: Igor Lacík
Registration number: 2-SRA-2014-288-Q-R
Duration of the project: 09.2014 - 08.2016
Cooperating institutions: University of Illinois, Chicago, USA (Prof Oberholzer, Coordinator), NTNU Trondheim, Norway

Slovak Research and Development Agency (APVV)

Silicon carbide thin film technologies: Research and development of silicon carbide thin film technologies for application in solar cells and thin film devices
Project APVV
Principal investigator: Angela Kleinová
Registration number: APVV-0443-12
Duration of the project: 10.2013 - 12.2016
Cooperating institutions: Institute of Chemistry SAS Bratislava (Coordinator, J. Huran)

Materials and processes for functional encapsulation of pancreatic islets in diabetes treatment(MEREDIT)
Project APVV
Principal investigator: Igor Lacík
Other investigators: Rastislav Baran, Angela Kleinová, Daniela Moravčíková, Nadežda Petrenčíková, Juraj Kronek, Filip Rázga, Petra Šrámková, Anna Zahoranová, Lucia Kleščíková, Andrea Mihálová, Veronika Némethová, Petra Mazancová, Anna Chovancová, Zuzana Kroneková, Dušana Treľová, Lucia Uhelská
Registration number: APVV-14-0858
Duration of the project: 07.2015 - 06.2016
Cooperating institutions: Medzinárodné laserové centrum, Bratislava, SVK; University of Illinois, Chicago, USA; Centre of Molecular Inflamation Research, NTNU, Trondheim, NOR; Politecnico di Milano, Milano, ITA

Imobilizované rekombinantné mikroorganizmy pre biotechnologickú produkciu chemických špecialít pomocou biokatalytických kaskádových reakcií(IRENKA)
Project APVV
Principal investigator: I. Lacík
Registration number: APVV-15-0227
Duration of the project: 11.-0001 - 11.-0001
Cooperating institutions: Chemický ústav SAV, FCHPT STU Bratislava

Scientific Grant Agency (VEGA)

Biocompatibility study of polymers and polymeric materials suitable for biomedical applications. In vitro analysis of cytotoxicity and cell response at the signal trasduction level.
Project VEGA
Principal investigator: Zuzana Kroneková
Registration number: VEGA 2/0156/15
Duration of the project: 01.2015 - 12.2017

Polymers based on 2-oxazolines for targeted drug delivery and controlled cell adhesion
Project VEGA
Principal investigator: Juraj Kronek
Registration number: VEGA 2/0163/15
Duration of the project: 01.2015 - 12.2017

Kinetics and bioapplications of zwitterionic polymers
Project VEGA
Principal investigator: Igor Lacík
Registration number: VEGA 2/0198/14
Duration of the project: 01.2014 - 12.2016

MNT-ERA-Net Projects

M2Neural: Multifunctional Materials for Advanced Neural Interfaces(M-ERA.NET Transnational Call 2013)
Project ERANET
Principal investigator: Igor Lacík
Registration number: M-ERA.NET 11/2014
Duration of the project: 11.2014 - 10.2016
Cooperating institutions: The BioRobotics Institute, Scuola Superiore di Studi Universitari e di Perfezionamento Sant’Anna, Pisa, Italy (Coordinator of the project: Arianna Menciassi)

SASPRO

Conjugated antisense system for selective and specific BCR-ABL suppression: An innovative strategy for CML treatment(CASSETTE)
Project SASPRO
Principal investigator: Filip Rázga
Registration number: 0057/01/02
Duration of the project: 04.2015 - 03.2018