Projects DBR

Recent projects

BASF

Kinetic coefficients and models for polymerization processes: co- and terpolymerization studies in water, alcohols and their mixtures
Project BASF
Principal investigator: Lacík Igor, Robin Hutchinson (Queen’s University, Kingston, Canada)
Registration number: R & D kontrakt
Duration of the project: 07.2019 – 06.2022
Cooperating institutions: Queen’s University, Kingston, Canada

Slovak Research and Development Agency (APVV)

Immobilization and co-immobilization of viable whole-cell biocatalysts with enzyme cascades for production of chemical specialties, development of methods for their characterization and bioreactor engineering
Project APVV
Principal investigator: Marek Bučko (FCHPT STU), Lacík Igor
Registration number: APVV-20-0272
Duration of the project: 07.2021 – 06.2026
Cooperating institutions: FCHPT STU Bratislava

Activation of the VGF/BDNF/TrkB pathway by synthetic mRNA encapsulated in polyplex nanoparticles: effects on neural excitability, neuroplasticity and animal behavior
Project APVV
Principal investigator: Eliahu Dremencov (Centre of Bioscences SAS), Juraj Kronek
Registration number: APVV-20-0202
Duration of the project: 07.2021 – 06.2025
Cooperating institutions: Centre of Bioscences SAS, Biomedical Research Centre SAS

Polymer materials based on poly(2-alkyl-2-oxazolines) and polyphosphazenes with tuneable thermosensitivity and biodegradation
Project APVV
Principal investigator: Juraj Kronek
Registration number: APVV-SK-AT-20-0025
Duration of the project: 01.2021 – 12.2022
Cooperating institutions: Centre of Bioscences SAS, Biomedical Research Centre SAS

Rational design of hydrogel microcapsules for immunoprotection of transplanted pancreatic islets in diabetes treatment (MICROPAN)
Project APVV
Principal investigator: Igor Lacík
Registration number: APVV-18-0480
Duration of the project: 07.2019 – 06.2023
Cooperating institutions: International Laser Centre, Bratislava; Institute of Physics SAS

Bionanocomposites based on organic polycations and layered silicates
Project APVV
Principal investigator: Jana Madejová (Institute of Inorganic Chemistry SAS), Juraj Kronek
Registration number: APVV-19-0487
Duration of the project: 07.2020 – 06.2024
Cooperating institutions: Institute of Inorganic Chemistry SAS

Scientific Grant Agency (VEGA)

Development of immunoactive polymer carriers for photodynamic therapy
Project VEGA
Principal investigator: Zuzana Kroneková
Registration number: VEGA 2/0172/21
Duration of the project: 01.2021 – 12.2023

Preparation and study of polymer gels for protection of cultural heritage
Project VEGA
Principal investigator: Milena Reháková (FCHPT STU), Juraj Kronek
Registration number: VEGA 1/0602/19
Duration of the project: 01.2019 – 12.2022
Cooperating institutions: FCHPT STU Bratislava

Microspheres based on dual non-covalently and covalently crosslinked alginates with self-healing properties for cell encapsulation
Project VEGA
Principal investigator: Abolfazl Heydari
Registration number: VEGA 2/0140/20
Duration of the project: 01.2020 – 12.2022

Radical polymerization of water-soluble monomers: the effect of molecular interactions on the polymerization kinetics and mechanism
Project VEGA
Principal investigator: Igor Lacík
Registration number: VEGA 2/0121/20
Duration of the project: 01.2020 – 12.2022

MAD

Implantable polymeric drug delivery devices based on dual non-covalent and covalent crosslinking network with self-healing properties
Project MAD
Principal investigator: Abolfazl Heydari
Registration number: MAD
Duration of the project: 01.2021 – 12.2022
Cooperating institutions: Department of Pharmaceutical Tecnology, Hacettepe University, Turkey

COST

Advanced Engineering and Research of aeroGels for Environment and Life Sciences
Project COST EÚ
Principal investigator: Igor Lacík
Registration number: COST Action CA18125
Duration of the project: 04.2019 – 04.2023
Cooperating intitutions: 37 total, University of Natural Resources and Life Sciences Vienna (BOKU), Austria, UCLouvain, Belgium, University of Liege, Belgium, Faculty of Chemical Engineering and Technology, Zagreb, Croatia, Universidad de Santiago de Compostela, Santiago de Compostela, Spain, VSB-Technical University of Ostrava, Czech Republic, University of Helsinki, Finland, Centre for Materials Forming (CEMEF), Sophia-Antipolis, France, …

Previous projects

BASF

Kinetic coefficients and models for existing and future polymerization processes and systems at BASF
Project BASF
Principal investigator: Igor Lacík
Registration number: projekt BASF AG, Ludwigshafen, Nemecko
Duration of the project: 09.2015 – 08.2018
Cooperating institutions: Queens University, Kingston (Prof. R. Hutchinson)

Determination of rate coefficients of water-soluble monomers with special emphasis on charged/ionizable monomers
Project BASF
Principal investigator: Igor Lacík
Registration number: BASF 06/2004
Duration of the project: 06.2004 – 05.2015
Cooperating institutions: Institute of Physical Chemistry, Göttingen, Germany (Prof. M. Buback), Queen’s University, Kingston (Prof. R. Hutchinson) and Eidgenössische Technische Hochschule, Zürich, Switzerland (Prof. G. Storti)

Jouvenile Diabetes Research Foundation. JDRF Grant

New generation PMCG multicomponent microcapsule with tailored biointerface to avoid the immune response after transplantation
Project JDRF
Principal investigator: Igor Lacík
Registration number: 2-SRA-2018-521-S-B
Duration of the project: 09.2017 – 08.2020
Cooperating institutions: CellTrans, Inc., Chicago, USA (Prof Oberholzer), NTNU Trondheim, Norway, UMCh Prague, CZ

Multicomponent microcapsules for allogeneic islet transplantation in a comprehensive, preclinical non-human primate model
Project JDRF
Principal investigator: Igor Lacík
Registration number: 2-SRA-2014-288-Q-R
Duration of the project: 09.2014 – 08.2016
Cooperating institutions: University of Illinois, Chicago, USA (Prof Oberholzer, Coordinator), NTNU Trondheim, Norway

Slovak Research and Development Agency (APVV)

Immobilized recombinant microorganisms for the biotechnological production of chemical specialties using biocatalytic cascade reactions (IRENKA)
Project APVV
Principal investigator: I. Lacík
Registration number: APVV-15-0227
Duration of the project: 07.2016 – 06.2020
Cooperating institutions: Institute of Chemistry SAS, Bratislava; The Faculty of Chemical and Food Technology STU, Bratislava

Nanocomposite materials based on organo-phosphonium smectits and polymers (Nanomat)
Project APVV
Principal investigator: I. Chodák
Registration number: APVV-15-0741
Duration of the project: 07.2016 – 06.2020
Cooperating institutions: Institute of Inorganic Chemistry SAS, Bratislava

Towards highly seletive cancer treatment: Endogenous lipoprotein-DARPin complexes as a new generation of targeted drug delivery vehicles (DARLINK)
Project APVV
Principal investigator: I. Lacík, J. Kronek
Registration number: APVV-15-0485
Duration of the project: 07.2016 – 06.2020
Cooperating institutions: Faculty of Science, Pavol Jozef Šafárik University in Košice; INSTITUTE OF ANIMAL BIOCHEMISTRY AND GENETICS CBS SAS; Faculty of Medicine, University of Comenius

The design and characterization of hybrid polymeric scavengers for endotoxins (HYBRID)
Project APVV
Principal investigator: Juraj Kronek
Registration number: APVV-SK-KR-18-0011
Duration of the project: 09.2018 – 12.2019
Cooperating institutions: Hanyang University, Seoul, Republic of Korea

Materials and processes for functional encapsulation of pancreatic islets in diabetes treatment (MEREDIT)
Project APVV
Principal investigator: Igor Lacík
Registration number: APVV-14-0858
Duration of the project: 07.2015 – 06.2019
Cooperating institutions: International Laser Centre

Silicon carbide thin film technologies: Research and development of silicon carbide thin film technologies for application in solar cells and thin film devices
Project APVV
Principal investigator: Angela Kleinová
Registration number: APVV-0443-12
Duration of the project: 10.2013 – 12.2016
Cooperating institutions: Institute of Chemistry SAS Bratislava (Coordinator, J. Huran)

Materials and processes for functional encapsulation of pancreatic islets in diabetes treatment (MEREDIT)
Project APVV
Principal investigator: Igor Lacík
Other investigators: Rastislav Baran, Angela Kleinová, Daniela Moravčíková, Nadežda Petrenčíková, Juraj Kronek, Filip Rázga, Petra Šrámková, Anna Zahoranová, Lucia Kleščíková, Andrea Mihálová, Veronika Némethová, Petra Mazancová, Anna Chovancová, Zuzana Kroneková, Dušana Treľová, Lucia Uhelská
Registration number: APVV-14-0858
Duration of the project: 07.2015 – 06.2016
Cooperating institutions: Medzinárodné laserové centrum, Bratislava, SVK; University of Illinois, Chicago, USA; Centre of Molecular Inflamation Research, NTNU, Trondheim, NOR; Politecnico di Milano, Milano, ITA

Scientific Grant Agency (VEGA)

Combined polymer systems for cancer immunotherapy
Project VEGA
Principal investigator: Zuzana Kroneková
Registration number: VEGA 2/0124/18
Duration of the project: 01.2018 – 12.2020

Preparation of polymeric microspheres via internal gelation in emulsion and critical evaluation of their properties toward functional treatment of type I diabetes
Project VEGA
Principal investigator: Dušana Treľová
Registration number: VEGA 2/0059/16
Duration of the project: 01.2016 – 12.2018

Biocompatibility study of polymers and polymeric materials suitable for biomedical applications. In vitro analysis of cytotoxicity and cell response at the signal trasduction level.
Project VEGA
Principal investigator: Zuzana Kroneková
Registration number: VEGA 2/0156/15
Duration of the project: 01.2015 – 12.2017

Polymers based on 2-oxazolines for targeted drug delivery and controlled cell adhesion
Project VEGA
Principal investigator: Juraj Kronek
Registration number: VEGA 2/0163/15
Duration of the project: 01.2015 – 12.2017

Kinetics and bioapplications of zwitterionic polymers
Project VEGA
Principal investigator: Igor Lacík
Registration number: VEGA 2/0198/14
Duration of the project: 01.2014 – 12.2016

MNT-ERA-Net Projects

M2Neural: Multifunctional Materials for Advanced Neural Interfaces (M-ERA.NET Transnational Call 2013)
Project ERANET
Principal investigator: Igor Lacík
Registration number: M-ERA.NET 11/2014
Duration of the project: 11.2014 – 10.2016
Cooperating institutions: The BioRobotics Institute, Scuola Superiore di Studi Universitari e di Perfezionamento Sant’Anna, Pisa, Italy (Coordinator of the project: Arianna Menciassi)

SASPRO

Conjugated antisense system for selective and specific BCR-ABL suppression: An innovative strategy for CML treatment (CASSETTE)
Project SASPRO
Principal investigator: Filip Rázga
Registration number: 0057/01/02
Duration of the project: 04.2015 – 03.2018

Other Projects

Cationic poly(2-oxazolines) for gene delivery and drug delivery applications
Project OP
Principal investigator: Juraj Kronek
Registration number: MAD
Duration of the project: 01.2018 – 12.2020
Cooperating institutions: Institute of Polymers BAS Sofia

Characterization of polymers and microcapsules (Otsuka Pharmaceutical Factory, Inc, Japan)
Project OP
Principal investigator: Lacík Igor
Duration of the project: 01.2017 – 12.2020

Development of biocompatible stimuli-responsive drug delivery systems comprising copolymers of 2-oxazoline and 3-hydroxybutyrate (Vyšegradský fond vedecké štipendium)
Project OP
Principal investigator: Michal Kawalec (CMPW PAN Zabrze), Juraj Kronek
Duration of the project: 01.2020 – 10.2020
Cooperating institutions: CMPW PAN Zabrze

Testing of multicomponent PMCG microcapsules in the NHP pre-clinical model
Project OP
Principal investigator: Lacík Igor
Duration of the project: 01.2018 – 08.2019
Cooperating institutions: CellTrans Inc., Chicago